October 16, 2025
Sometimes, recovery from a scar can require more patience than the original wound healing. A lot of products might promise fading of the marks and smoothing of the skin surface. However, recently, retinol has become one of the most talked-about ingredients in scar care. In this blog, we’ll explore the science behind retinol in scar creams, how it should (or shouldn’t) be used, and how Scar Protocol integrates retinol.
Before deciding if retinol is “a must-have,” it's important to understand why it's included in scar creams. Retinoids (vitamin A derivatives) are known to influence dermal remodeling. They can support skin remodeling by boosting collagen production, activating fibroblasts, and improving the organization of collagen fibers. In a study, adapalene 0.3% applied over months showed improvement in scar texture and grade.
Retinoids also accelerate epidermal turnover, which can help smooth surface irregularities, reduce hyperpigmentation, and disperse melanin granules. They also inhibit melanosome transfer, aiding in the fading of post-inflammatory pigmentation often seen in scars.
So, retinol is not universally mandatory in scar creams, but it can be a powerful component when timed and used judiciously.
If you’re going to include retinol (or retinoid derivatives) in your scar regimen, here are some best practices you can follow.
We believe in respecting the biology of wound healing and scar maturation. That’s why in our system, retinol arrives at the right time.
Scar healing isn’t a single-step process, it’s a gradual, biological sequence that requires the right care at each stage. The Scar Protocol system was developed to guide this process by providing targeted ingredients at the exact time your skin needs them most.
Below is an overview of the five phases, each designed to support the skin’s recovery from early healing to long-term remodeling.
Phase
Focus
Key Ingredients
Phase I
Moisturize & cleanse
Phase II
Moisture support
Phase III
Repair & hydrate
Phase IV
Skin conditioning
Phase V
Collagen remodeling
Phase V is designed for the final stage of scar healing in our 12-month incision scar recovery system. With retinol as its core active, this last phase supports the skin’s deeper remodeling process at a time when the scar is largely healed but still evolving beneath the surface. Because we've paced prior phases to prepare the skin, Phase V’s formula is designed to optimize the healing environment safely, even if you've never used retinol before. Have questions about which phase your scar is ready for? Give us a call at 425-864-3777 for a complimentary scar consultation.
Use low concentrations as suggested by your provider for scar care. Higher strengths can irritate healing skin.
Yes, if introduced too soon or applied too often. Start retinol only after full healing and use gentle, hydrating formulations.
You may notice gradual texture and tone improvements within 8–12 weeks. Scar remodeling is slow, continuing for months, so consistency and patience, along with proper sun protection, are essential.